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FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants
There is great interest in increasing proteins’ stability to enhance their utility as biocatalysts, therapeutics, diagnostics and nanomaterials. Directed evolution is a powerful, but experimentally strenuous approach. Computational methods offer attractive alternatives. However, due to the limited r...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631455/ https://ncbi.nlm.nih.gov/pubmed/26529612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004556 |
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