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Pharmacokinetics and pharmacodynamics of rilotumumab: a decade of experience in preclinical and clinical cancer research

Rilotumumab is a fully human monoclonal antibody against hepatocyte growth factor, the only known ligand of the MET receptor. Over the last decade, rilotumumab has been extensively tested in preclinical studies and in clinical studies in a variety of cancer types. In this review, we examine the phar...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Zhang, Y, Doshi, S, Zhu, M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631169/
https://ncbi.nlm.nih.gov/pubmed/25912961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12663
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