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Pharmacokinetics and pharmacodynamics of rilotumumab: a decade of experience in preclinical and clinical cancer research

Rilotumumab is a fully human monoclonal antibody against hepatocyte growth factor, the only known ligand of the MET receptor. Over the last decade, rilotumumab has been extensively tested in preclinical studies and in clinical studies in a variety of cancer types. In this review, we examine the phar...

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Библиографические подробности
Опубликовано в: :Br J Clin Pharmacol
Главные авторы: Zhang, Y, Doshi, S, Zhu, M
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley & Sons, Ltd 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631169/
https://ncbi.nlm.nih.gov/pubmed/25912961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12663
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