Bat and pig IFN-induced transmembrane protein 3 restrict cell entry by influenza virus and lyssaviruses

IFN-induced transmembrane protein 3 (IFITM3) is a restriction factor that blocks cytosolic entry of numerous viruses that utilize acidic endosomal entry pathways. In humans and mice, IFITM3 limits influenza-induced morbidity and mortality. Although many IFITM3-sensitive viruses are zoonotic, whether...

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Bibliografiske detaljer
Udgivet i:J Gen Virol
Main Authors: Benfield, Camilla T. O., Smith, Sarah E., Wright, Edward, Wash, Rachael S., Ferrara, Francesca, Temperton, Nigel J., Kellam, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Society for General Microbiology 2015
Fag:
Animal
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631062/
https://ncbi.nlm.nih.gov/pubmed/25614588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.000058
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