CD40 Engagement Triggers Switching to IgA1 and IgA2 in Human B Cells Through Induction of Endogenous TGF-β: Evidence for TGF-β But Not IL-10-Dependent Direct Sμ→Sα and Sequential Sμ→Sγ, Sγ→Sα DNA Recombination()

IgA are major effectors of antimicrobial defense in the respiratory and digestive tracts. We have analyzed the requirements for and the modalities of switching to IgA using our recently identified monoclonal model of human germinal center differentiation, CL-01 B cells. CL-01 cells bear surface IgM...

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Vydáno v:J Immunol
Hlavní autoři: Zan, Hong, Cerutti, Andrea, Dramitinos, Patricia, Schaffer, András, Casali, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: 1998
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631047/
https://ncbi.nlm.nih.gov/pubmed/9820493
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