Redirection of Epithelial Immune Responses by Short-Chain Fatty Acids through Inhibition of Histone Deacetylases

Short-chain fatty acids (SCFAs) are products of microbial fermentation that are important for intestinal epithelial health. Here, we describe that SCFAs have rapid and reversible effects on toll-like receptor (TLR) responses in epithelial cells. Incubation of HEK293 or HeLa epithelial cells with the...

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Опубликовано в: :Front Immunol
Главные авторы: Lin, May Young, de Zoete, Marcel R., van Putten, Jos P. M., Strijbis, Karin
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2015
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630660/
https://ncbi.nlm.nih.gov/pubmed/26579129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00554
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