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NFAT isoforms play distinct roles in TNFα-induced retinal leukostasis

The objective of this study was to determine the role of individual NFAT isoforms in TNFα-induced retinal leukostasis. To this end, human retinal microvascular endothelial cells (HRMEC) transfected with siRNA targeting individual NFAT isoforms were treated with TNFα, and qRT-PCR was used to examine...

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Pubblicato in:Sci Rep
Autori principali: Bretz, Colin A., Savage, Sara R., Capozzi, Megan E., Suarez, Sandra, Penn, John S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630625/
https://ncbi.nlm.nih.gov/pubmed/26527057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14963
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