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The Peroxisome Proliferator-Activated Receptor-β/δ antagonist GSK0660 mitigates Retinal Cell Inflammation and Leukostasis

Diabetic retinopathy (DR) is triggered by retinal cell damage stimulated by the diabetic milieu, including increased levels of intraocular free fatty acids. Free fatty acids may serve as an initiator of inflammatory cytokine release from Müller cells, and the resulting cytokines are potent stimulato...

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Detalles Bibliográficos
Publicado en:Exp Eye Res
Main Authors: Capozzi, Megan E., Savage, Sara R., McCollum, Gary W., Hammer, Sandra S., Ramos, Carla J., Yang, Rong, Bretz, Colin A., Penn, John S.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7426872/
https://ncbi.nlm.nih.gov/pubmed/31758977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2019.107885
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