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Effect of a 5-lipoxygenase inhibitor on leukotriene generation and airway responses after allergen challenge in asthmatic patients.

The effect of a single oral dose (800 mg) of zileuton (A-64077), a specific 5-lipoxygenase inhibitor, on the early and late airway responses to inhaled allergen was studied in a randomised, double blind, placebo controlled, and crossover trial in nine subjects with atopic asthma. Leukotriene generat...

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Detalhes bibliográficos
Main Authors: Hui, K P, Taylor, I K, Taylor, G W, Rubin, P, Kesterson, J, Barnes, N C, Barnes, P J
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC463027/
https://ncbi.nlm.nih.gov/pubmed/1851340
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