Depletion of macrophages in CD11b diphtheria toxin receptor mice induces brain inflammation and enhances inflammatory signaling during traumatic brain injury

Immune cells have important roles during disease and are known to contribute to secondary, inflammation-induced injury after traumatic brain injury. To delineate the functional role of macrophages during traumatic brain injury, we depleted macrophages using transgenic CD11b-DTR mice and subjected th...

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Publicado no:Brain Res
Main Authors: Frieler, Ryan A., Nadimpalli, Sameera, Boland, Lauren K., Xie, Angela, Kooistra, Laura J., Song, Jianrui, Chung, Yutein, Cho, Kae Won, Lumeng, Carey N., Wang, Michael M., Mortensen, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630151/
https://ncbi.nlm.nih.gov/pubmed/26208897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2015.07.011
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