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Association between telomere length and chromosome 21 nondisjunction in the oocyte

Chromosome 21 nondisjunction in oocytes is the most common cause of trisomy 21, the primary chromosomal abnormality responsible for Down syndrome (DS). This specific type of error is estimated to account for over 90% of live births with DS, with maternal age being the best known risk factor for chro...

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Detalhes bibliográficos
Publicado no:Hum Genet
Main Authors: Albizua, I, Rambo-Martin, BL, Allen, EG, He, W, Amin, AS, Sherman, SL
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630140/
https://ncbi.nlm.nih.gov/pubmed/26407969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-015-1603-0
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