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TIM-3, a Possible Target for Immunotherapy in Cancer and Chronic Viral Infections

Effector T-cell responses are controlled by complex mechanisms involving various soluble factors and co-stimulatory and co-inhibitory molecules. These inhibitory receptors act as immune checkpoints and are extensively investigated as possible therapeutic targets, such as PD-1 and CTLA-4. Recently TI...

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Detalhes bibliográficos
Publicado no:Austin Virol Retro Virol
Main Authors: Tieu, Roger, Amancha, Praveen Kumar, Villinger, François, Byrareddy, Siddappa N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629856/
https://ncbi.nlm.nih.gov/pubmed/26539564
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