Sorting of Pmel17 to melanosomes through the plasma membrane by AP1 and AP2: evidence for the polarized nature of melanocytes

Adaptor proteins (AP) play important roles in the sorting of proteins from the trans-Golgi network, but how they function in the sorting of various melanosome-specific proteins such as Pmel17, an essential structural component of melanosomes, in melanocytes is unknown. We characterized the processin...

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Pubblicato in:J Cell Sci
Autori principali: Valencia, Julio C., Watabe, Hidenori, Chi, An, Rouzaud, Francois, Chen, Kevin G., Vieira, Wilfred D., Takahashi, Kaoruko, Yamaguchi, Yuji, Berens, Werner, Nagashima, Kunio, Shabanowitz, Jeffrey, Hunt, Donald F., Appella, Ettore, Hearing, Vincent J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629779/
https://ncbi.nlm.nih.gov/pubmed/16492709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.02804
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