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Mechanism of the nucleotidyl-transfer reaction in DNA polymerase revealed by time-resolved protein crystallography
Nucleotidyl-transfer reaction catalyzed by DNA polymerase is a fundamental enzymatic reaction for DNA synthesis. Until now, a number of structural and kinetic studies on DNA polymerases have proposed a two-metalion mechanism of the nucleotidyl-transfer reaction. However, the actual reaction process...
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| Pubblicato in: | Biophysics (Nagoya-shi) |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society of Japan (BSJ)
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4629682/ https://ncbi.nlm.nih.gov/pubmed/27493538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2142/biophysics.9.31 |
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