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Using ancestry matching to combine family-based and unrelated samples for genome-wide association studies()
We propose a method to analyze family-based samples together with unrelated cases and controls. The method builds on the idea of matched case–control analysis using conditional logistic regression (CLR). For each trio within the family, a case (the proband) and matched pseudo-controls are constructe...
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| Publié dans: | Stat Med |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4629477/ https://ncbi.nlm.nih.gov/pubmed/20862653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.4057 |
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