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Adenine: an important drug scaffold for the design of antiviral agents

Adenine derivatives, in particular the scaffold bearing the acyclic nucleoside phosphonates (ANPS), possess significant antiviral and cytostatic activity. Till now, several effective adenine derivatives have been marketed for the treatment of HIV, HBV, CMV and other virus-infected diseases. These co...

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Publicado en:Acta Pharm Sin B
Autores principales: Wang, Changyuan, Song, Zhendong, Yu, Haiqing, Liu, Kexin, Ma, Xiaodong
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629444/
https://ncbi.nlm.nih.gov/pubmed/26579473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2015.07.002
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