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Polycyclic compounds: Ideal drug scaffolds for the design of multiple mechanism drugs?

Recently there has been a resurging interest in developing multi-functional drugs to treat diseases with complex pathological mechanisms. Such drug molecules simultaneously target multiple etiologies that have been found to be important modulators in specific diseases. This approach has significant...

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Detalhes bibliográficos
Publicado no:Neurotherapeutics
Main Authors: Van der Schyf, Cornells J., Geldenhuys, Werner J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084265/
https://ncbi.nlm.nih.gov/pubmed/19110208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nurt.2008.10.037
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