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Pharmacokinetic analysis and tissue distribution of Vam3 in the rat by a validated LC-MS/MS method

Vam3 is a potential pharmacologically active ingredient isolated from Vitis amurensis Rupr. A rapid, simple and sensitive method to determine Vam3 levels in rat plasma and tissue was developed based on LC-MS/MS. Vam3 and an internal standard (IS) were chromatographed on a C18 short column with aceto...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Zhang, Ruixia, Mao, Ping, Zhang, Tingting, Ma, Chen, Jin, Bo, Li, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629264/
https://ncbi.nlm.nih.gov/pubmed/26579454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2015.03.011
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