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Generation of hypoxanthine phosphoribosyltransferase gene knockout rabbits by homologous recombination and gene trapping through somatic cell nuclear transfer

The rabbit is a common animal model that has been employed in studies on various human disorders, and the generation of genetically modified rabbit lines is highly desirable. Female rabbits have been successfully cloned from cumulus cells, and the somatic cell nuclear transfer (SCNT) technology is w...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yin, Mingru, Jiang, Weihua, Fang, Zhenfu, Kong, Pengcheng, Xing, Fengying, Li, Yao, Chen, Xuejin, Li, Shangang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629196/
https://ncbi.nlm.nih.gov/pubmed/26522387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16023
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