Amplification of hypoxanthine-guanine phosphoribosyltransferase genes in chromosome-mediated gene transferents.

Hypoxanthine-guanine phosphoribosyltransferase (HPRT) enzyme activities may be elevated in genetically unstable chromosome-mediated gene transferents selected for transfer of the HPRT gene. Increased levels of HPRT polypeptides in unstable mouse L cell gene transferents were demonstrated by two-dime...

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Hauptverfasser: Linder, S, Coleman, A W, Eisenstadt, J M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1984
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC368767/
https://ncbi.nlm.nih.gov/pubmed/6717438
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