Human induced pluripotent stem cell‐derived versus adult cardiomyocytes: an in silico electrophysiological study on effects of ionic current block

BACKGROUND AND PURPOSE: Two new technologies are likely to revolutionize cardiac safety and drug development: in vitro experiments on human‐induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CMs) and in silico human adult ventricular cardiomyocyte (hAdultV‐CM) models. Their combination was...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Br J Pharmacol
Main Authors: Paci, M, Hyttinen, J, Rodriguez, B, Severi, S
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Research Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629192/
https://ncbi.nlm.nih.gov/pubmed/26276951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13282
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