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Synthesis and biological evaluation of sophocarpinic acid derivatives as anti-HCV agents
Chronic hepatitis C virus (HCV) infection has become a major public health burden worldwide. Twenty-two sophocarpinic acid or matrine derivatives were synthesized and their anti-HCV activities were evaluated in vitro. The structure-activity analysis revealed that (i) sophocarpinic acids with a D-sec...
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| Publié dans: | Acta Pharm Sin B |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4629077/ https://ncbi.nlm.nih.gov/pubmed/26579400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2014.06.002 |
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