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Synthesis and biological evaluation of sophocarpinic acid derivatives as anti-HCV agents

Chronic hepatitis C virus (HCV) infection has become a major public health burden worldwide. Twenty-two sophocarpinic acid or matrine derivatives were synthesized and their anti-HCV activities were evaluated in vitro. The structure-activity analysis revealed that (i) sophocarpinic acids with a D-sec...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Acta Pharm Sin B
Main Authors: Li, Yinghong, Peng, Zonggen, Gao, Limei, Song, Danqing
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629077/
https://ncbi.nlm.nih.gov/pubmed/26579400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2014.06.002
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