The role of inducible nitric oxide synthase for interstitial remodeling of alveolar septa in surfactant protein D-deficient mice

Surfactant protein D (SP-D) modulates the lung's immune system. Its absence leads to NOS2-independent alveolar lipoproteinosis and NOS2-dependent chronic inflammation, which is critical for early emphysematous remodeling. With aging, SP-D knockout mice develop an additional interstitial fibroti...

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Publicat a:Am J Physiol Lung Cell Mol Physiol
Autors principals: Knudsen, Lars, Atochina-Vasserman, Elena N., Massa, Christopher B., Birkelbach, Bastian, Guo, Chang-Jiang, Scott, Pamela, Haenni, Beat, Beers, Michael F., Ochs, Matthias, Gow, Andrew J.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628984/
https://ncbi.nlm.nih.gov/pubmed/26320150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00017.2015
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