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Selective Inhibition of Inducible NO Synthase Activity In Vivo Reverses Inflammatory Abnormalities in Surfactant Protein D-Deficient Mice()

Surfactant protein D (SP-D)-deficient (SP-D(−/−)) mice exhibit early development of emphysema. Previously we have shown that SP-D deficiency results in increased production and activity of inducible NO synthase (iNOS). In this study, we examined whether treatment with the iNOS inhibitor 1400W could...

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Detalhes bibliográficos
Main Authors: Atochina-Vasserman, Elena N., Beers, Michael F., Kadire, Helchem, Tomer, Yaniv, Inch, Adam, Scott, Pamela, Guo, Chang J., Gow, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009628/
https://ncbi.nlm.nih.gov/pubmed/18056350
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