Activation of protein kinase Cα increases phosphorylation of the UT-A1 urea transporter at serine 494 in the inner medullary collecting duct

Hypertonicity increases urea transport, as well as the phosphorylation and membrane accumulation of UT-A1, the transporter responsible for urea permeability in the inner medullary collect duct (IMCD). Hypertonicity stimulates urea transport through PKC-mediated phosphorylation. To determine whether...

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Publicado no:Am J Physiol Cell Physiol
Main Authors: Blount, Mitsi A., Cipriani, Penelope, Redd, Sara K., Ordas, Ronald J., Black, Lauren N., Gumina, Diane L., Hoban, Carol A., Klein, Janet D., Sands, Jeff M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628937/
https://ncbi.nlm.nih.gov/pubmed/26333598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00171.2014
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