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The Ying and Yang of STAT3 in Human Disease
The transcription factor signal transducer and activator of transcription 3 (STAT3) is a critical regulator of multiple, diverse cellular processes. Heterozgyous, germline, loss-of-function mutations in STAT3 lead to the primary immune deficiency Hyper-IgE syndrome. Heterozygous, somatic, gain-of-fu...
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| Published in: | J Clin Immunol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4628878/ https://ncbi.nlm.nih.gov/pubmed/26280891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-015-0187-8 |
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