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The gut microbiome as a target for regulatory T cell-based immunotherapy: induction of regulatory lymphocytes by oral administration of anti-LPS enriched colostrum alleviates immune mediated colitis
BACKGROUND: Gut-derived bacterial endotoxin is an important cofactor in the pathogenesis of IBD. Regulatory T cells (Tregs) are essential for maintenance of peripheral tolerance and can prevent and alleviate IBD. To determine the immune modulatory effect of anti-LPS enriched hyperimmune colostrum, i...
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發表在: | BMC Gastroenterol |
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Main Authors: | , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
BioMed Central
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4628342/ https://ncbi.nlm.nih.gov/pubmed/26518263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-015-0388-x |
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