The gut microbiome as a target for regulatory T cell-based immunotherapy: induction of regulatory lymphocytes by oral administration of anti-LPS enriched colostrum alleviates immune mediated colitis

BACKGROUND: Gut-derived bacterial endotoxin is an important cofactor in the pathogenesis of IBD. Regulatory T cells (Tregs) are essential for maintenance of peripheral tolerance and can prevent and alleviate IBD. To determine the immune modulatory effect of anti-LPS enriched hyperimmune colostrum, i...

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Detalhes bibliográficos
Publicado no:BMC Gastroenterol
Main Authors: Yaʼacov, Ami Ben, Lichtenstein, Yoav, Zolotarov, Lidya, Ilan, Yaron
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628342/
https://ncbi.nlm.nih.gov/pubmed/26518263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-015-0388-x
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