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Global Transcriptome Analysis Reveals That Poly(ADP-Ribose) Polymerase 1 Regulates Gene Expression through EZH2

Posttranslational modifications, such as poly(ADP-ribosyl)ation (PARylation), regulate chromatin-modifying enzymes, ultimately affecting gene expression. This study explores the role of poly(ADP-ribose) polymerase (PARP) on global gene expression in a lymphoblastoid B cell line. We found that inhibi...

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Bibliografiska uppgifter
I publikationen:Mol Cell Biol
Huvudupphovsmän: Martin, Kayla A., Cesaroni, Matteo, Denny, Michael F., Lupey, Lena N., Tempera, Italo
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628063/
https://ncbi.nlm.nih.gov/pubmed/26370511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00635-15
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