Promoter methylation of TRIM9 as a marker for detection of circulating tumor DNA in breast cancer patients

The aim of the present study was to investigate the promoter methylation status of TRIM9 in breast cancer and to determine the presence of TRIM9-methylated circulating tumor DNA (ctDNA) in plasma. Bisulfite sequencing with a next generation sequencer showed TRIM9 promoter methylation in 92 % (11/12)...

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Bibliografiske detaljer
Udgivet i:Springerplus
Main Authors: Mishima, Chieko, Kagara, Naofumi, Matsui, Saki, Tanei, Tomonori, Naoi, Yasuto, Shimoda, Masafumi, Shimomura, Atsushi, Shimazu, Kenzo, Kim, Seung Jin, Noguchi, Shinzaburo
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627990/
https://ncbi.nlm.nih.gov/pubmed/26543769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-015-1423-7
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