BRCA1 promoter methylation of normal breast epithelial cells as a possible precursor for BRCA1-methylated breast cancer

The breast cancer susceptibility gene 1 (BRCA1) and glutathione S-transferase P1 (GSTP1) promoters are reportedly often methylated in breast cancer tissues. Their methylation status in surrounding normal breast tissues has not been examined thoroughly although this may well be important for a better...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Otani, Yoko, Miyake, Tomohiro, Kagara, Naofumi, Shimoda, Masafumi, Naoi, Yasuto, Maruyama, Naomi, Shimomura, Atsuhi, Shimazu, Kenzo, Kim, Seung Jin, Noguchi, Shinzaburo
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462354/
https://ncbi.nlm.nih.gov/pubmed/25155055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12506
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