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BRCA1 promoter methylation of normal breast epithelial cells as a possible precursor for BRCA1-methylated breast cancer

The breast cancer susceptibility gene 1 (BRCA1) and glutathione S-transferase P1 (GSTP1) promoters are reportedly often methylated in breast cancer tissues. Their methylation status in surrounding normal breast tissues has not been examined thoroughly although this may well be important for a better...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Sci
Hauptverfasser: Otani, Yoko, Miyake, Tomohiro, Kagara, Naofumi, Shimoda, Masafumi, Naoi, Yasuto, Maruyama, Naomi, Shimomura, Atsuhi, Shimazu, Kenzo, Kim, Seung Jin, Noguchi, Shinzaburo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462354/
https://ncbi.nlm.nih.gov/pubmed/25155055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12506
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