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LFA-1 is Critical for Regulatory T cell Homeostasis and Function

Cellular adhesion molecules involved in cell-to-cell mediated suppression by Tregs are not well characterized. We found that the majority of Tregs expressed LFA-1 but most strikingly that the frequency of Tregs in LFA-1(−/−) mice was significantly lower (~50%) in the spleen, lymph nodes, and Peyer’s...

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Detalhes bibliográficos
Publicado no:Mol Immunol
Main Authors: Wohler, Jillian, Bullard, Dan, Schoeb, Trent, Barnum, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627944/
https://ncbi.nlm.nih.gov/pubmed/19428111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.04.004
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