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Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass

Loss of pancreas β-cell function is the precipitating factor in all forms of diabetes. Cell replacement therapies, such as islet transplantation, remain the best hope for a cure; however, widespread implementation of this method is hampered by availability of donor tissue. Thus, strategies that expa...

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Detalles Bibliográficos
Publicado en:Mol Endocrinol
Main Authors: George, Nicholas M., Boerner, Brian P., Mir, Shakeel U. R., Guinn, Zachary, Sarvetnick, Nora E.
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627601/
https://ncbi.nlm.nih.gov/pubmed/26378466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1375
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