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Comparison of Deconvolution-Based and Absorption Modeling IVIVC for Extended Release Formulations of a BCS III Drug Development Candidate

In vitro–in vivo correlations (IVIVC) are predictive mathematical models describing the relationship between dissolution and plasma concentration for a given drug compound. The traditional deconvolution/convolution-based approach is the most common methodology to establish a level A IVIVC that provi...

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Detaylı Bibliyografya
Yayımlandı:AAPS J
Asıl Yazarlar: Kesisoglou, Filippos, Xia, Binfeng, Agrawal, Nancy G. B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627461/
https://ncbi.nlm.nih.gov/pubmed/26290380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9816-7
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