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Use of Preclinical Dog Studies and Absorption Modeling to Facilitate Late Stage Formulation Bridging for a BCS II Drug Candidate
Formulation changes are common during drug development either due to clinical or manufacturing considerations. These changes especially at later stages of drug development oftentimes raise questions on the potential impact of a new formulation on bioavailability. In this work, the preclinical assess...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3909157/ https://ncbi.nlm.nih.gov/pubmed/24022346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-0030-6 |
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