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Use of Preclinical Dog Studies and Absorption Modeling to Facilitate Late Stage Formulation Bridging for a BCS II Drug Candidate

Formulation changes are common during drug development either due to clinical or manufacturing considerations. These changes especially at later stages of drug development oftentimes raise questions on the potential impact of a new formulation on bioavailability. In this work, the preclinical assess...

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Kaydedildi:
Detaylı Bibliyografya
Yazar: Kesisoglou, Filippos
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909157/
https://ncbi.nlm.nih.gov/pubmed/24022346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-0030-6
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