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Regulation of VCP/p97 demonstrates the critical balance between cell death and epithelial-mesenchymal transition (EMT) downstream of ER stress

Valosin-containing protein (VCP), also called p97, is a AAA+ ATPase that has been shown to be involved in endoplasmic reticulum-associated protein degradation (ERAD), mitochondria quality control and vesicle transport. We and others have previously found that disruption of VCP is sufficient to cause...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Shah, Parag P., Beverly, Levi J.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627341/
https://ncbi.nlm.nih.gov/pubmed/25970786
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