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Common cytotoxic chemotherapeutics induce epithelial-mesenchymal transition (EMT) downstream of ER stress

Endoplasmic reticulum (ER) in eukaryotes is a main organelle involved in a wide variety of functions including calcium storage, lipid biosynthesis, protein folding and protein transport. Disruption of ER homeostasis leads to ER stress and activation of the unfolded protein response (UPR). We and oth...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Shah, Parag P., Dupre, Tess V., Siskind, Leah J., Beverly, Levi J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410250/
https://ncbi.nlm.nih.gov/pubmed/28186986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15150
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