Combined estrogenic and anti-estrogenic properties of estetrol on breast cancer may provide a safe therapeutic window for the treatment of menopausal symptoms

Increased risk of breast cancer is a critical side effect associated with the use of a menopausal hormone therapy (MHT). Estetrol (E4) is a natural estrogen produced by the human fetal liver and is a promising compound for clinical use in MHT. However, its impact on breast cancer is controversial an...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Gérard, Céline, Mestdagt, Mélanie, Tskitishvili, Ekaterine, Communal, Laudine, Gompel, Anne, Silva, Elisabete, Arnal, Jean-François, Lenfant, Françoise, Noel, Agnès, Foidart, Jean-Michel, Péqueux, Christel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627333/
https://ncbi.nlm.nih.gov/pubmed/26056044
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