Deletion of Smad3 improves cardiac allograft rejection in mice

T cells play a critical role in acute allograft rejection. TGF-β/Smad3 signaling is a key pathway in regulating T cell development. We report here that Smad3 is a key transcriptional factor of TGF-β signaling that differentially regulates T cell immune responses in a mouse model of cardiac allograft...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Wang, Ying-ying, Jiang, Hong, Wang, Yu-cheng, Huang, Xiao-ru, Pan, Jun, Yang, Chen, Shou, Zhang-fei, Xiang, Shi-long, Chen, Da-jin, Lan, Hui-yao, Chen, Jiang-hua
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper: Pathology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627288/
https://ncbi.nlm.nih.gov/pubmed/26219259
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky