Cynara scolymus affects malignant pleural mesothelioma by promoting apoptosis and restraining invasion

Malignant pleural mesothelioma is a poorly treated neoplasia arising from the pleural mesothelial lining. Here we document that the leaf extract of Cynara scolymus exerts broad antitumoral effects both in vitro and in vivo on mesothelioma cell lines. We found that Cynara scolymus treatment affects s...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Pulito, Claudio, Mori, Federica, Sacconi, Andrea, Casadei, Luca, Ferraiuolo, Maria, Valerio, Maria Cristina, Santoro, Raffaela, Goeman, Frauke, Maidecchi, Anna, Mattoli, Luisa, Manetti, Cesare, Di Agostino, Silvia, Muti, Paola, Blandino, Giovanni, Strano, Sabrina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627240/
https://ncbi.nlm.nih.gov/pubmed/26136339
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