Metformin-induced metabolic reprogramming of chemoresistant ALDH(bright) breast cancer cells

Metabolic remodeling is a hallmark of cancer progression and may affect tumor chemoresistance. Here we investigated by 1H-NMR/PCA analysis the metabolic profile of chemoresistant breast cancer cell subpopulations (ALDH(bright) cells) and their response to metformin, a promising anticancer metabolic...

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Hauptverfasser: Cioce, Mario, Valerio, MariaCristina, Casadei, Luca, Pulito, Claudio, Sacconi, Andrea, Mori, Federica, Biagioni, Francesca, Manetti, Cesare, Muti, Paola, Strano, Sabrina, Blandino, Giovanni
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147311/
https://ncbi.nlm.nih.gov/pubmed/24980829
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