Discovery of new small molecules inhibiting 67 kDa laminin receptor interaction with laminin and cancer cell invasion

The 67 kDa laminin receptor (67LR) is a non-integrin receptor for laminin (LM) that derives from a 37 kDa precursor (37LRP). 67LR expression is increased in neoplastic cells and correlates with an enhanced invasive and metastatic potential. We used structure-based virtual screening (SB-VS) to search...

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Publicat a:Oncotarget
Autors principals: Pesapane, Ada, Di Giovanni, Carmen, Rossi, Francesca Wanda, Alfano, Daniela, Formisano, Luigi, Ragno, Pia, Selleri, Carmine, Montuori, Nunzia, Lavecchia, Antonio
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627239/
https://ncbi.nlm.nih.gov/pubmed/26062445
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