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APP Maturation and Intracellular Localization Are Controlled by a Specific Inhibitor of 37/67 kDa Laminin-1 Receptor in Neuronal Cells

Amyloid precursor protein (APP) is processed along both the nonamyloidogenic pathway preventing amyloid beta peptide (Aβ) production and the amyloidogenic pathway, generating Aβ, whose accumulation characterizes Alzheimer’s disease. Items of evidence report that the intracellular trafficking plays a...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bhattacharya, Antaripa, Limone, Adriana, Napolitano, Filomena, Cerchia, Carmen, Parisi, Silvia, Minopoli, Giuseppina, Montuori, Nunzia, Lavecchia, Antonio, Sarnataro, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084285/
https://ncbi.nlm.nih.gov/pubmed/32143270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051738
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