Curcumin suppresses cell growth and invasion and induces apoptosis by down-regulation of Skp2 pathway in glioma cells

Studies have demonstrated that curcumin exerts its tumor suppressor function in a variety of human cancers including glioma. However, the exact underlying molecular mechanisms remain obscure. Emerging evidence has revealed that Skp2 (S-phase kinase associated protein 2) plays an oncogenic role in tu...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Wang, Lixia, Ye, Xiantao, Cai, Xingming, Su, Jingna, Ma, Renqiang, Yin, Xuyuan, Zhou, Xiuxia, Li, Huabin, Wang, Zhiwei
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627233/
https://ncbi.nlm.nih.gov/pubmed/26046466
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