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Rottlerin inhibits cell growth and invasion via down-regulation of Cdc20 in glioma cells

Rottlerin, isolated from a medicinal plant Mallotus phillippinensis, has been demonstrated to inhibit cellular growth and induce cytoxicity in glioblastoma cell lines through inhibition of calmodulin-dependent protein kinase III. Emerging evidence suggests that rottlerin exerts its antitumor activit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Wang, Lixia, Hou, Yingying, Yin, Xuyuan, Su, Jingna, Zhao, Zhe, Ye, Xiantao, Zhou, Xiuxia, Zhou, Li, Wang, Zhiwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342514/
https://ncbi.nlm.nih.gov/pubmed/27626499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11974
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