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The Effects of Shiga Toxin 1, 2 and Their Subunits on Cytokine and Chemokine Expression by Human Macrophage-Like THP-1 Cells

Infection by Shiga toxin (Stx)-producing enterohemorrhagic Escherichia coli (EHEC) results in severe diarrhea, hemorrhagic colitis, and, occasionally, hemolytic-uremic syndrome (HUS). HUS is associated with an increase in pro-inflammatory cytokines and chemokines, many of which are produced by macro...

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Bibliografiske detaljer
Udgivet i:Toxins (Basel)
Main Authors: Brandelli, Jeremy R., Griener, Thomas P., Laing, Austin, Mulvey, George, Armstrong, Glen D.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626720/
https://ncbi.nlm.nih.gov/pubmed/26473922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7104054
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