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Recombinant Shiga Toxin B-Subunit-Keyhole Limpet Hemocyanin Conjugate Vaccine Protects Mice from Shigatoxemia

Enterohemorrhagic Escherichia coli (EHEC) causes hemorrhagic colitis in humans and, in a subgroup of infected subjects, a more serious condition called hemolytic-uremic syndrome (HUS). These conditions arise because EHEC produces two antigenically distinct forms of Shiga toxin (Stx), called Stx1 and...

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Bibliographic Details
Main Authors: Marcato, Paola, Griener, Thomas P., Mulvey, George L., Armstrong, Glen D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230940/
https://ncbi.nlm.nih.gov/pubmed/16177326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6523-6529.2005
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