Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells

The discovery of new bioactive compounds from marine natural sources is very important in pharmacological research. Here we developed a Wnt responsive luciferase reporter assay to screen small molecule inhibitors of cancer associated constitutive Wnt signaling pathway. We identified that gliotoxin (...

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Publicat a:Mar Drugs
Autors principals: Chen, Junxiong, Wang, Chenliang, Lan, Wenjian, Huang, Chunying, Lin, Mengmeng, Wang, Zhongyang, Liang, Wanling, Iwamoto, Aikichi, Yang, Xiangling, Liu, Huanliang
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626688/
https://ncbi.nlm.nih.gov/pubmed/26445050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13106259
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