JNK signaling pathway is involved in piperlongumine-mediated apoptosis in human colorectal cancer HCT116 cells

Piperlongumine (PPLGM), an alkaloid isolated from the long pepper (Piper longum L.), can selectively trigger cancer cell death in colorectal cancer cells. The present study investigated whether the c-Jun NH(2)-terminal kinase (JNK) signaling pathway is involved in PPLGM-induced apoptosis in the huma...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: LI, WEN, WEN, CHUANGYU, BAI, HAIYAN, WANG, XIAOYAN, ZHANG, XIAOLI, HUANG, LANLAN, YANG, XIANGLING, IWAMOTO, AIKICHI, LIU, HUANLIANG
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509051/
https://ncbi.nlm.nih.gov/pubmed/26622558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3371
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